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  • Title: [Immunological effectiveness of secondary revaccination against tetanus performed at prolonged intervals].
    Author: Maksimova NM, Basova NN, Sukhorukova NL, Finkel' MP.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1987 Jun; (6):43-6. PubMed ID: 3307239.
    Abstract:
    After primary immunization with adsorbed DPT vaccine antitetanus immunity was retained for 9-10 years in 90.6-98.4% of children covered by this study. The second booster immunization of children against tetanus with adsorbed DT toxoid with reduced antigen content, made at an interval prolonged to 7-10 years under the conditions of lower antitoxic immunity, ensured a high level of intense antitetanus immunity. These data point to the possibility of prolonging the interval between booster immunizations to 9-10 years and reducing the number of injections and antigenic load.
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