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  • Title: Reactive Eccrine Syringofibroadenomatosis Associated With Venous Leg Ulcers: A Case Report and Literature Review.
    Author: Tedbirt B, Carvalho P, Boulard C, Tetart F, Deschamps-Huvier A, Chenal P, Courville P, Cellier L, Joly P.
    Journal: Int J Low Extrem Wounds; 2023 Mar; 22(1):135-138. PubMed ID: 33076722.
    Abstract:
    Eccrine syringofibroadenoma (ESFA) is a rare adnexal tumor deriving from the acrosyringeal portion of the eccrine duct. Five subtypes of ESFA were described including a reactive form. Reactive ESFAs are associated with inflammatory and neoplastic dermatoses. In this article, we report the case of a 90-year-old woman presenting with 3 leg ulcers evolving for 2 years surrounded by large verrucous and eczematous lesions. Multiple skin biopsies showed anastomosing epithelial cords connected to the epidermis consistent with ESFA. We identified 8 cases of ESFA associated with chronic leg ulcers in the literature and reviewed their main clinical and histological features.
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