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  • Title: [Pharmacokinetics of pefloxacin in burn patients].
    Author: Potel G, Meignier M, Touzé MD, Montay G, Drugeon HB, Baron D.
    Journal: Pathol Biol (Paris); 1987 Jun; 35(5 Pt 2):777-80. PubMed ID: 3309814.
    Abstract:
    The aim of this study was to evaluate pharmacokinetics of pefloxacin (PFL) in burn patients (n = 11), compared with 5 non burned subjects. The role of the extent of the burn and the delay after initial thermal trauma were also evaluated. Our results suggest that neither the extent of the burn, nor the delay of the study play a role. Compared with non-burned subjects, burn patients exhibit a shorter elimination half-life, but modifications in dosage regimen are not required.
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