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  • Title: Optic nerve hypoplasia.
    Author: Lambert SR, Hoyt CS, Narahara MH.
    Journal: Surv Ophthalmol; 1987; 32(1):1-9. PubMed ID: 3310293.
    Abstract:
    Optic nerve hypoplasia is an easily overlooked, nonprogressive developmental anomaly which results in a wide range of visual deficits. It is frequently associated with clinically significant central nervous system and endocrine abnormalities. Maternal substance abuse is increasingly recognized in many cases. A supranormal regression of optic nerve axons in utero, rather than a primary failure of differentiation, is proposed as the pathogenesis.
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