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  • Title: [Differentiation of lymphocyte populations in the blood of breast-cancer patients].
    Author: Weber W, Nagel GA, Obrist R, Nagel E, Heitz P, Oberholzer M, Herzig D.
    Journal: Schweiz Med Wochenschr; 1977 Jul 16; 107(28):1010-2. PubMed ID: 331468.
    Abstract:
    The number of T lymphocytes has been determined in the peripheral blood of 90 women (65 patients with breast cancer and 25 healthy controls) using a sheep-erythrocyte rosetting technique and a cytochemical method for intracellular localization of a nonspecific acid esterase. Both tests were in agreement in showing a significant depression of T-cell percentage in a group of patients with progressive disseminated breast cancer under hormonal and chemotherapeutic treatment. After radiotherapy a fall in T cells was observed only with the rosetting method. Possible reasons for this phenomenon are discussed.
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