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  • Title: Exercise-based rehabilitation strategies in heart transplant recipients: Focus on high-intensity interval training.
    Author: Masarone D, Melillo E, Petraio A, Valente F, Gravino R, Verrengia M, Pacileo G.
    Journal: Clin Transplant; 2021 Feb; 35(2):e14143. PubMed ID: 33150597.
    Abstract:
    Despite progressive improvement in medical therapy and standard care, the exercise capacity of heart transplant recipients is reduced compared with age-matched healthy individuals. Exercise-based rehabilitation programs have been shown to improve the exercise capacity of transplant patients through a multifactorial effect. In this context, high-intensity interval exercise is a growing field of research, with current evidence suggesting a major benefit in heart transplant recipients compared with a conventional training protocol. Therefore, this study aimed to provide an overview of the mechanisms involved in the reduced exercise capacity of heart transplant patients and a review of current rehabilitation strategies with a special focus on the mechanisms and clinical effects of high-intensity interval training exercise.
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