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  • Title: Toward low-voltage dielectrophoresis-based microfluidic systems: A review.
    Author: Ramirez-Murillo CJ, de Los Santos-Ramirez JM, Perez-Gonzalez VH.
    Journal: Electrophoresis; 2021 Mar; 42(5):565-587. PubMed ID: 33166414.
    Abstract:
    Dielectrophoretically driven microfluidic devices have demonstrated great applicability in biomedical engineering, diagnostic medicine, and biological research. One of the potential fields of application for this technology is in point-of-care (POC) devices, ideally allowing for portable, fully integrated, easy to use, low-cost diagnostic platforms. Two main approaches exist to induce dielectrophoresis (DEP) on suspended particles, that is, electrode-based DEP and insulator-based DEP, each featuring different advantages and disadvantages. However, a shared concern lies in the input voltage used to generate the electric field necessary for DEP to take place. Therefore, input voltage can determine portability of a microfluidic device. This review outlines the recent advances in reducing stimulation voltage requirements in DEP-driven microfluidics.
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