These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The kinetoplast immunofluorescence technic using Crithidia luciliae, a simple test for the detection of DNA-antibodies].
    Author: Lange CE, Schmid-Hannak I, Sennekamp J.
    Journal: Z Hautkr; 1977 Aug 15; 52(16):831-6. PubMed ID: 331704.
    Abstract:
    The kinetoplast immunofluorescence test for the detection of antibodies against desoxynucleic acid (DNA) utilizes as a substrate the native double-stranded DNA containing kinetoplast of the hemoflagellate Crithidia luciliae, which is nonpathogenic in human beings. By studying the sera of 279 patients with dermatological and internal diseases, as well as the sera of 80 blood donors, this technique was assessed for its usefulness in routine diagnosis. DNA-antibodies were found most frequently in the sera of patients with systemic lupus erythematosus (34/53). Additionally DNA-antibodies were demonstrated in some patients with cicatrical pemphigoid (1/1), autoimmune hepatitis (4/25) and myasthenia gravis (1/3). According to the experience thus far the kinetoplast immunofluorescence test appears to be a specific and well reproducible method to demonstrate DNA-antibodies in a simple way.
    [Abstract] [Full Text] [Related] [New Search]