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  • Title: Immunogenicity of yeast-derived hepatitis B vaccines in young adults.
    Author: Bergamini F, Zanetti A.
    Journal: Postgrad Med J; 1987; 63 Suppl 2():137-8. PubMed ID: 3317349.
    Abstract:
    A study of the safety and immunogenicity of two different recombinant DNA yeast-derived hepatitis B vaccines was conducted in 90 young adults according to a 0-, 1-, and 6-month vaccination schedule. Preliminary results using the 20 micrograms SmithKline Biologicals or 10 micrograms Merck Sharp & Dohme recombinant yeast-derived hepatitis B vaccines indicate that both vaccines are clinically safe and immunogenic. Only minor side effects have thus far been reported. Seroconversion rates among vaccine recipients were 80% or greater after the first two injections with either vaccine, and 100% after the third dose of the SmithKline Biologicals recombinant DNA hepatitis B vaccine.
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