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  • Title: [Characteristics of the ultrastructural organization of the nuclei of somatic cell hybrids].
    Author: Kerkis AIu, Kazanskaia GM, Zhdanova NS, Khristoliubova NB.
    Journal: Tsitologiia; 1987 Dec; 29(12):1355-9. PubMed ID: 3327213.
    Abstract:
    A study was made of the ultrastructure of cell nuclei of two types of hybrid clones obtained from the fusion of Chinese hamster with human skin fibroblasts, and from that of mouse hepatoma cells with mink fibroblasts. In cell nuclei of the eight hybrid clones deep invaginations of the inner membrane, not characteristic of the parent cells, were revealed. Analysis of serial sections, and application of electron microscopic radioautography and histochemistry have suggested that these structures are associated with the nuclear envelope which is necessary for regulating the superfluous chromosome localization in the hybrid nucleus.
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