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  • Title: Non-enzymatic glucose sensor based on a g-C3N4/NiO/CuO nanocomposite.
    Author: Lotfi Z, Gholivand MB, Shamsipur M.
    Journal: Anal Biochem; 2021 Mar 01; 616():114062. PubMed ID: 33285122.
    Abstract:
    In this paper, a non-enzymatic glucose sensor was developed based on a g-C3N4/NiO/CuO nanocomposite immobilized on a glassy carbon electrode (GCE). Field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Brunauer-Emmett-Teller (BET) were utilized for the characterization of the synthesized g-C3N4/NiO/CuO nanocomposite. The electrocatalytic activity of the nanocomposite was investigated by cyclic voltammetry, and the amperometric technique was applied for monitoring glucose. The g-C3N4/NiO/CuO/GCE exhibited better electrocatalytic performance than g-C3N4/GCE, g-C3N4/CuO/GCE and g-C3N4/NiO/GCE. Under optimized conditions, the proposed sensor offered a linearity ranging from 0.4 μM to 8.5 mM with a detection limit of 0.1 μM and a sensitivity of 362.12 μA mM-1 cm-2. The constructed sensor displayed favorable reproducibility, outstanding selectivity, and long-term performance. These results reveal that the sensor is a promising candidate for blood glucose sensing.
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