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  • Title: The effects of noise on histological measures of the cochlear vasculature and red blood cells: a review.
    Author: Axelsson A, Dengerink H.
    Journal: Hear Res; 1987 Dec; 31(2):183-91. PubMed ID: 3328745.
    Abstract:
    This paper compiles the results from seven experiments which have investigated noise exposure effects on histological measures of the cochlear vasculature and red blood cells. Two of these studies included at least two experimental conditions and all evaluated numerous histological parameters in several cochlear vessels. The combined results suggest that noise has a consistent general effect of reducing apparent cochlear blood flow as indicated by decreased RBC density, increased aggregation of RBCs, increased variability in RBC density, decreased number of RBC columns, increased vessel lumen irregularity and encroachment of perivascular cells upon the lumen wall. When considered at the level of the individual vessels, however, inconsistent results were observed. Fewer effects were noted in experiments which permitted animals to survive after the noise exposure than in those which sacrificed the animals immediately. Impulse noise resulted in more frequent vascular sequelae than did continuous noise. Further, impulse noise more frequently influenced vessels of the external wall than did continuous noise.
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