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  • Title: A robust ECG denoising technique using variable frequency complex demodulation.
    Author: Hossain MB, Bashar SK, Lazaro J, Reljin N, Noh Y, Chon KH.
    Journal: Comput Methods Programs Biomed; 2021 Mar; 200():105856. PubMed ID: 33309076.
    Abstract:
    BACKGROUND AND OBJECTIVE: Electrocardiogram (ECG) is widely used for the detection and diagnosis of cardiac arrhythmias such as atrial fibrillation. Most of the computer-based automatic cardiac abnormality detection algorithms require accurate identification of ECG components such as QRS complexes in order to provide a reliable result. However, ECGs are often contaminated by noise and artifacts, especially if they are obtained using wearable sensors, therefore, identification of accurate QRS complexes often becomes challenging. Most of the existing denoising methods were validated using simulated noise added to a clean ECG signal and they did not consider authentically noisy ECG signals. Moreover, many of them are model-dependent and sampling-frequency dependent and require a large amount of computational time. METHODS: This paper presents a novel ECG denoising technique using the variable frequency complex demodulation (VFCDM) algorithm, which considers noises from a variety of sources. We used the sub-band decomposition of the noise-contaminated ECG signals using VFCDM to remove the noise components so that better-quality ECGs could be reconstructed. An adaptive automated masking is proposed in order to preserve the QRS complexes while removing the unnecessary noise components. Finally, the ECG was reconstructed using a dynamic reconstruction rule based on automatic identification of the severity of the noise contamination. The ECG signal quality was further improved by removing baseline drift and smoothing via adaptive mean filtering. RESULTS: Evaluation results on the standard MIT-BIH Arrhythmia database suggest that the proposed denoising technique provides superior denoising performance compared to studies in the literature. Moreover, the proposed method was validated using real-life noise sources collected from the noise stress test database (NSTDB) and data from an armband ECG device which contains significant muscle artifacts. Results from both the wearable armband ECG data and NSTDB data suggest that the proposed denoising method provides significantly better performance in terms of accurate QRS complex detection and signal to noise ratio (SNR) improvement when compared to some of the recent existing denoising algorithms. CONCLUSIONS: The detailed qualitative and quantitative analysis demonstrated that the proposed denoising method has been robust in filtering varieties of noises present in the ECG. The QRS detection performance of the denoised armband ECG signals indicates that the proposed denoising method has the potential to increase the amount of usable armband ECG data, thus, the armband device with the proposed denoising method could be used for long term monitoring of atrial fibrillation.
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