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  • Title: Innovative drug delivery systems in cardiovascular medicine: nifedipine-GITS and clonidine-TTS.
    Author: Frishman WH, Sherman D, Feinfeld DA.
    Journal: Cardiol Clin; 1987 Nov; 5(4):703-16. PubMed ID: 3331321.
    Abstract:
    Innovative drug delivery systems have been developed for nifedipine and clonidine that prolong the pharmacologic activity of the medications, allowing once daily dosing. The nifedipine-GITS (gastrointestinal therapeutic system) tablet formulation and the clonidine-TTS (transcutaneous delivery system) patch may also reduce side effects in patients while preserving the therapeutic efficacy of the origin drug formulations (nifedipie capsule, clonidine tablet).
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