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  • Title: Comparison of the efficacy of metagenomic next-generation sequencing and Xpert MTB/RIF in the diagnosis of tuberculous meningitis.
    Author: Yu G, Wang X, Zhu P, Shen Y, Zhao W, Zhou L.
    Journal: J Microbiol Methods; 2021 Jan; 180():106124. PubMed ID: 33321144.
    Abstract:
    Metagenomic next-generation sequencing (mNGS) is an emerging sequence-based method that detects genomic information of pathogenic microorganisms from a wide range of clinical specimens. The mNGS has moderate sensitivity and very high specificity for tuberculous meningitis, and the validity of mNGS was higher than that of Xpert MTB/RIF.
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