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  • Title: A Screen-Printed Electrode Modified With Graphene/Co3O4 Nanocomposite for Electrochemical Detection of Tramadol.
    Author: Aflatoonian MR, Tajik S, Aflatoonian B, Beitollahi H, Zhang K, Le QV, Cha JH, Jang HW, Shokouhimehr M, Peng W.
    Journal: Front Chem; 2020; 8():562308. PubMed ID: 33330356.
    Abstract:
    In this paper, graphene (Gr)/Co3O4 nanocomposite was synthesized and utilized for the development of a novel electrochemical sensor to detect tramadol. Tramadol determination was examined by linear sweep voltammetry, differential pulse voltammetry, cyclic voltammetry, and chronoamperometry on Gr/Co3O4 nanocomposite-modified screen-printed electrode (Gr/Co3O4/SPE) in phosphate-buffered saline (PBS). Under the optimized condition, the detection limit of tramadol is 0.03 μM (S/N = 3) in the linear ranges of 0.1-500.0 μM. Furthermore, Gr/Co3O4/SPE was satisfactorily utilized to detect tramadol in tramadol tablet and urine specimens.
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