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  • Title: RNA-ligant interactions. (I) Magnesium binding sites in yeast tRNAPhe.
    Author: Holbrook SR, Sussman JL, Warrant RW, Church GM, Kim SH.
    Journal: Nucleic Acids Res; 1977 Aug; 4(8):2811-20. PubMed ID: 333395.
    Abstract:
    X-ray crystallagraphic studies studies indicate that there are at least four site-specifically bound hydrated Mg2+ ions, [Mg(H2O)n]2+, in yeast tRNAPhe. The size and the octahedral coordination geometry, rather than the charge, of [Mg(H2O)N]2+ appear to be the primary reasons for the specificity of magnesium ions in site-binding and in the stabilization of the tertiary structure of tRNA.
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