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  • Title: Assay of 2-hydroxyputrescine in various regions of rat brain by gas chromatography-mass spectrometry.
    Author: Noto T, Hasegawa T, Hashimoto H, Nakajima T.
    Journal: J Neurochem; 1988 Feb; 50(2):464-7. PubMed ID: 3335858.
    Abstract:
    2-Hydroxyputrescine in seven regions of single rat brains was measured with a sensitive, specific assay by gas chromatography-mass spectrometry. The regions were the cerebral cortex, cerebellum, medulla oblongata, hypothalamus, striatum, hippocampus, and midbrain. The level of 2-hydroxyputrescine was very high in the cerebral cortex and cerebellum, high in the medulla oblongata, hypothalamus, and hippocampus, and low in the striatum and midbrain. The level of 2-hydroxyputrescine in the cerebellum was significantly higher than in the striatum and midbrain.
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