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  • Title: Charcoal bezoar. Small-bowel obstruction secondary to amitriptyline overdose therapy.
    Author: Ray MJ, Radin DR, Condie JD, Halls JM.
    Journal: Dig Dis Sci; 1988 Jan; 33(1):106-7. PubMed ID: 3338352.
    Abstract:
    Nasogastric administration of activated charcoal is effective in decreasing the half-life of amitriptyline. A case is reported in which this therapy for amitriptyline overdose led to charcoal bezoar formation and small-bowel obstruction. Amitriptyline's atropinic side effects on the gut make this a possible complication in such patients.
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