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  • Title: Clinical regression of amyloid nephropathy in a patient with rheumatoid arthritis. A case report.
    Author: Mody GM, Meyers OL.
    Journal: S Afr Med J; 1988 Jan 09; 73(1):55-6. PubMed ID: 3340903.
    Abstract:
    A 22-year-old woman with active seronegative rheumatoid arthritis responded to intramuscular gold but developed proteinuria which settled when this therapy was stopped. Proteinuria recurred after 2 weeks of penicillamine therapy but settled when this regimen was stopped. Six months later she developed a nephrotic syndrome and rectal and renal biopsies showed evidence of amyloidosis. She was treated with chlorambucil for 1 year and the disease activity was well controlled. There was regression of the nephrotic syndrome and her serum albumin and renal function are normal 6 years later.
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