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  • Title: Decreases of cortical and thalamic glucose metabolism produced by parietal cortex stimulation in the rat.
    Author: Sharp JW, Gonzalez MF, Morton MT, Simon RP, Sharp FR.
    Journal: Brain Res; 1988 Jan 12; 438(1-2):357-62. PubMed ID: 3345443.
    Abstract:
    Parietal cortex stimulation elicited focal decreases as well as increases of brain glucose metabolism in ipsilateral cortex, ipsilateral thalamus, and contralateral cortex of rats in a pattern resembling 'surround inhibition'. It is proposed that parietal stimulation activated inhibitory circuits which decreased cortical and thalamic glucose metabolism. This decrease of cerebral glucose metabolism is important for interpreting brain glucose metabolic studies particularly when metabolic changes do not correlate with changes of neuronal activity.
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