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  • Title: [A cytologic diagnosis of breast secretions--application of cytology to the mass survey of breast cancer].
    Author: Fujii M, Ishii Y, Nagao M, Wakabayashi T, Fukahori S, Goto A, Tomono T, Hagiwara K.
    Journal: Gan No Rinsho; 1988 Feb; 34(2):174-8. PubMed ID: 3346995.
    Abstract:
    From January 1982 to March 1987, an exfoliative cytological examination of abnormal nipple discharge was carried out on 790 patients. Of 22 histologically confirmed mammary carcinomas, 7 cases (31.8%) were diagnosed as positive by conventional cytologic techniques. By using the concentration method, in which the nipple secretion was collected in a series of testings that lasted 3 to 5 days and stored in a glass tube containing a fixative, the diagnostic accuracy was seen to increase significantly and 9 out of 15 malignant cases (60.0%) were accurately diagnosed as having cancer. Moreover, all 5 cases without any palpable mass were found to be positive by the smears made by this procedure.
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