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  • Title: Lymphocytic interstitial pneumonia of common variable immunodeficiency.
    Author: Popa V.
    Journal: Ann Allergy; 1988 Mar; 60(3):203-6. PubMed ID: 3348496.
    Abstract:
    We report the beneficial effect of steroids in a 27-year-old woman with lymphocytic interstitial pneumonitis (LIP) and common variable immunodeficiency (CVID). Exertional dyspnea, x-ray infiltrates, and pulmonary physiologic abnormalities decreased or increased during 3 1/2 years of follow-up in parallel with the administered dose of prednisone. This observation rules out concomitant spontaneous remission as the explanation of steroid-induced improvement of LIP in CVID. Steroid treatment was apparently safe: the frequency and severity of recurrent bronchial infections did not change, although IgG replacement therapy was not provided.
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