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  • Title: [C-reactive protein, lactate and LDH isoenzymes in the cerebrospinal fluid in the diagnosis in childhood meningitis].
    Author: Castro-Gago M, Couce ML, Losada MC, González MC, Novo I, España MR, Rodríguez-Segade S.
    Journal: An Esp Pediatr; 1988 Jan; 28(1):31-3. PubMed ID: 3348555.
    Abstract:
    C reactive protein lactate and LDH isoenzymes were quantified in CSF of 32 children with meningitis (27 bacterial and 5 viral). Results in cases with bacterial meningitis were as follows. C reactive protein sensitivity was 11.1% and specificity was 100%. Lactate sensitivity was 33.3% and its specificity was 80%. LDH1 and LDH5 had a sensitivity of 44.4%, and specificities of 100 and 60% respectively. Considering these results an has believe that none of these tests is definitive in diagnosis of bacterial meningitis in children.
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