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  • Title: [Role of the stromal microenvironment in regulating bone marrow hemopoiesis under stress].
    Author: Gol'dberg ED, Dygaĭ AM, Zaritskiĭ AIu, Ivasenko IN, Shakhov VP.
    Journal: Biull Eksp Biol Med; 1988 Mar; 105(3):270-2. PubMed ID: 3349163.
    Abstract:
    The role of stromal microenvironment in bone marrow hemopoiesis during stress has been studied. The stimulation of functional activity of stromal cells, responsible for the transfer of hemopoiesis-inducing microenvironment has been found. The time required for the development of microenvironment coincide with the moment of T-lymphocyte appearance in the bone marrow. The induction of microenvironment preceded the development of hemopoiesis hyperplasia at the level of committed precursor cells of myelopoiesis and their more mature, morphologically differentiated progeny.
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