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  • Title: Familial double testicular tumors: identical chromosome changes in seminoma and embryonal carcinoma of the same testis.
    Author: Haddad FS, Sorini PM, Somsin AA, Nathan MH, Dobbs RM, Berger CS, Sandberg AA.
    Journal: J Urol; 1988 Apr; 139(4):748-50. PubMed ID: 3352038.
    Abstract:
    An identical abnormal chromosome, i(12p), and a marker chromosome of unknown origin were seen in 2 tumors of different histology (seminoma and embryonal carcinoma) in the same testis. A younger brother of the patient also had undergone orchiectomy for 2 seminomas in the left testis 2 years previously. These findings are discussed in relation to the possible cellular background of testicular tumors and their genetic parameters.
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