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  • Title: Age-dependent differences in cholinergic drug response in two strains of mice.
    Author: Castellano C, Oliverio A, Schwab C, Brueckner G, Biesold D.
    Journal: Neurosci Lett; 1988 Feb 03; 84(3):335-8. PubMed ID: 3352959.
    Abstract:
    The behavioral effects of nicotine and oxotremorine were assessed in two strains of mice, C57BL/6 (C57) and DBA/2 (DBA), differing in the ontogeny of forebrain cholinergic structures. Both nicotine and oxotremorine depressed to a higher extent the behavior of DBA mice starting at day 45 of postnatal life.
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