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  • Title: Atypical Cellular Blue Nevus With Necrosis Mimicking Melanoma Ex-Blue Nevus.
    Author: Henning A, Billings S, Ko J, Weaver J.
    Journal: Am J Dermatopathol; 2021 May 01; 43(5):e61-e64. PubMed ID: 33534207.
    Abstract:
    Histologic distinction between melanoma ex-blue nevus and cellular blue nevus (CBN) can often be difficult, but features supporting melanoma include infiltrative growth pattern, frequent mitoses, cytologic atypia and pleomorphism, cell crowding, and tumor necrosis. Unfortunately, these features are not constantly dependable and frequently borderline lesions exist, so-called atypical CBN, which lack explicit malignant features. Furthermore, some CBN and atypical CBN show an assortment of features, which may lead to their misdiagnosis as melanoma, but to date necrosis is generally absent. We present an unusual case of an atypical cellular blue nevus with extensive necrosis mimicking melanoma ex-blue nevus.
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