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  • Title: Dissimilar social cognition signatures in remitted schizophrenia and bipolar disorder.
    Author: Mehta UM, Punith M, Kumar CN, Kumar JK, Reddy YJ, Thirthalli J.
    Journal: Asian J Psychiatr; 2021 Mar; 57():102593. PubMed ID: 33581371.
    Abstract:
    In the light of shared genetic underpinnings of schizophrenia and bipolar disorder, their comparative profile of social cognition (SC) performance - an intermittent phenotype and determinant of functional outcome - is poorly understood. Using data from 160 individuals, we identify unique patterns of composite and domain-specific SC-abilities between these groups after controlling for their neurocognition. Individuals with schizophrenia and not bipolar disorder demonstrated deficits in composite SC-measures, which were not associated with their functional status. While patients with bipolar disorder had significantly lower scores on emotion recognition, they outperformed the healthy and schizophrenia groups on the second-order theory of mind.
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