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  • Title: Behavioral and morphological effects of oculomotor nucleus lesion on abducens internuclear neurons in the cat.
    Author: Delgado-Garciá JM, Escudero M, Torres B, Portillo F, Pásaro R.
    Journal: Brain Res; 1988 Mar 08; 443(1-2):333-7. PubMed ID: 3359273.
    Abstract:
    The activity of identified control and injured abducens internuclear neurons was recorded during spontaneous eye movements in the alert cat. From 2 days following the electrocoagulation of the contralateral oculomotor nucleus, abducens internuclear neurons showed a quick fatigability during eye fixations not observed in controls. Discharge rate during saccades started after the beginning of the eye movement and showed a fast exponential-like decay. These abnormal responses were not further recorded from 20 days following the lesion. Morphological studies indicated that 90% of the abducens internuclear neuron population disappeared 2 months following the lesion and showed no sign of recovery one year later.
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