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  • Title: A class of water-soluble Fe(III) coordination complexes as T1-weighted MRI contrast agents.
    Author: Wang R, An L, He J, Li M, Jiao J, Yang S.
    Journal: J Mater Chem B; 2021 Feb 25; 9(7):1787-1791. PubMed ID: 33595044.
    Abstract:
    Iron-based coordination complexes are showing increasing potential to be alternatives for T1-weighted magnetic resonance imaging (MRI) and contribute to the safety of gadolinium-based compounds. In this work, three water-soluble iron-based complexes constructed using catechol ligands exhibiting T1-weighted MRI contrast behavior are described. The longitudinal relaxivity (r1) increase from 0.88 to 1.43 mM-1 s-1 mainly depends on the sizes and the number of water molecules in the second and outer spheres around the discrete complexes.
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