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  • Title: Acute Disseminated Encephalomyelitis (ADEM): A Demyelinating Disease with Specific Morphological Features.
    Author: Cordier F, Velthof L, Creytens D, Van Dorpe J.
    Journal: Int J Surg Pathol; 2021 Jun; 29(4):392-394. PubMed ID: 33616454.
    Abstract:
    Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated inflammatory and demyelinating disorder of the central nervous system. Its characteristic perivenular demyelination and inflammation aid in the differential diagnosis with other inflammatory demyelinating diseases. Here, we present a clinical case of ADEM, summarize its histological hallmarks, and discuss pitfalls concerning the most important neuropathological differential diagnoses.
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