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  • Title: Evaluating the safety and efficacy of compression sutures with intracameral perfluoropropane (C3F8) in the management of acute corneal hydrops.
    Author: Vohra V, Shetty R, James E, Kundu G, D'Souza S.
    Journal: Int Ophthalmol; 2021 Jun; 41(6):2027-2031. PubMed ID: 33616834.
    Abstract:
    BACKGROUND: To evaluate the safety and efficacy of using corneal compression sutures with intracameral perfluoropropane (C3F8) in patients presenting with acute corneal hydrops in ectatic disorders. METHODS: A retrospective analysis was done for 43 eyes of patients of acute corneal hydrops, managed using a combination of intracameral 14% C3F8 and full-thickness compression sutures. Time for resolution of edema, corneal thickness (CT) change on anterior segment ocular coherence tomography (ASOCT), and visual outcomes were assessed. RESULTS: Corneal edema resolved with a mean duration of 14.8 ± 3.5 days (range 10-21). The mean CT on ASOCT decreased from a mean of 1437 µm (689-2770 µm) preoperatively to 543 µm (434 -66 µm) on the complete resolution of corneal edema. CONCLUSION: Our results suggest that full-thickness compression sutures and intracameral C3F8 injection can restore the imperviousness of posterior stroma. This technique appears to be a safe and effective technique for faster resolution of corneal edema post hydrops.
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