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  • Title: [Prognostic significance of different variants of chest pain in men aged 40-49 years (data of a prospective study)].
    Author: Shal'nova SA, Maksimov AB, Kapustina AV, Zhukovskiĭ GS, Varlamova TA.
    Journal: Ter Arkh; 1988; 60(1):30-5. PubMed ID: 3363504.
    Abstract:
    In a prospective study of males aged 40 to 59 without typical angina of effort in accordance with a cardiological questionnaire as well as major and minor ECG changes of ischemic type an average period of observation was 8.2 yrs. Three variants were analyzed: I--the absence of chest pains, II--the presence of chest pains unrelated to effort, III--untypical chest pains in physical exercise. The intensity of end points (fatal and nonfatal myocardial infarctions) was 8% (I), 6.9% (II), 11.7% (III) annually (the intensity of end points for typical angina of effort was 29%). The examinees of the 1st group were characterized by higher levels of HDLP cholesterol and BP, a lower body mass index, and smoked more than the examinees of the 2nd group however there were no differences in age, the levels of total cholesterol and triglycerides between these two groups. A relative risk of development of fatal MI was 1.9-fold higher in the 1st group than in the 2nd group. At the same time a relative risk of development of nonfatal MI was 1.25-fold lower in the 1st group than in the 2nd group.
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