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  • Title: Squamous mucosa overlying columnar epithelium in Barrett's esophagus in the absence of anti-reflux surgery.
    Author: Sampliner RE, Steinbronn K, Garewal HS, Riddell RH.
    Journal: Am J Gastroenterol; 1988 May; 83(5):510-2. PubMed ID: 3364411.
    Abstract:
    Seven of 45 patients with Barrett's esophagus prospectively followed with yearly endoscopy had histological evidence of squamous mucosa overlying Barrett's epithelium. This histological finding has previously been identified as a rare sequela of anti-reflux surgery. All seven patients had specialized columnar epithelium. No evidence of the overlying mucosa was recognized at endoscopy. Only one patient had previous anti-reflux surgery. During the observation interval, three patients had a decrease, and four had no change in the length of Barrett's epithelium. Squamous mucosa overlying columnar epithelium in Barrett's esophagus is not infrequent, and prior anti-reflux surgery is not a necessary precondition.
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