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Title: Structural and molecular mechanisms for membrane protein biogenesis by the Oxa1 superfamily. Author: McDowell MA, Heimes M, Sinning I. Journal: Nat Struct Mol Biol; 2021 Mar; 28(3):234-239. PubMed ID: 33664512. Abstract: Members of the Oxa1 superfamily perform membrane protein insertion in bacteria, the eukaryotic endoplasmic reticulum (ER), and endosymbiotic organelles. Here, we review recent structures of the three ER-resident insertases and discuss the extent to which structure and function are conserved with their bacterial counterpart YidC.[Abstract] [Full Text] [Related] [New Search]