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Title: Human sperm chromosome studies in a reciprocal translocation t(2;5). Author: Templado C, Navarro J, Benet J, Genescà A, Pérez MM, Egozcue J. Journal: Hum Genet; 1988 May; 79(1):24-8. PubMed ID: 3366459. Abstract: Sperm chromosome complements have been studied in a man heterozygous for a reciprocal translocation t(2;5)(p11;q15). Human sperm chromosomes were obtained after fertilization of zona-free hamster eggs. A total of 75 human sperm metaphases were analysed. On the complements studied, 59 (78.6%) resulted from a 2:2 segregation and 16 (21.3%) from a 3:1 segregation, 4:0 segregation was not observed. Our results indicate that at least 36% of sperm complements were unbalanced with respect to the translocation. The frequency of other chromosome anomalies unrelated to the translocation was 16%.[Abstract] [Full Text] [Related] [New Search]