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  • Title: Malignant pleural effusion treated by tetracycline sclerotherapy. A comparison of single vs repeated instillation.
    Author: Landvater L, Hix WR, Mills M, Siegel RS, Aaron BL.
    Journal: Chest; 1988 Jun; 93(6):1196-8. PubMed ID: 3371098.
    Abstract:
    Fifty patients with malignant pleural effusion were randomized to receive one or two doses of tetracycline sclerotherapy. We found that a single sclerotherapy treatment with tetracycline at a dose of 20 mg/kg was as effective as two sclerotherapy treatments and provided symptomatic relief in 46 of the 50 patients.
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