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  • Title: Acinar Melanosis of the Bartholin Gland: A Report of 3 Cases.
    Author: Khera KM, Moghimi A, Cataldo L, Kumar B, Gibbs PM.
    Journal: Int J Gynecol Pathol; 2022 Jan 01; 41(1):93-97. PubMed ID: 33720081.
    Abstract:
    Melanocytic pigmentation occurs in multiple sites in the lower female genital tract, but is rare within benign cysts of the vulva. We report 3 patients with multiloculated cystic lesions of the vulvar vestibule exhibiting prominent melanocytic pigmentation. The current cases differ from a previous report of melanosis in a Bartholin gland cyst in that the population of melanocytes occupies the acinar structures of the gland, rather than a squamous-lined surface. A similar cell population is demonstrated by immunoperoxidase methods in a fourth patient's nonpigmented gland, suggesting that melanin production may arise in a native, rather than metaplastic, cell population.
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