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  • Title: [Determinants of local tumor control in interstitial radiotherapy of prostatic cancer].
    Author: Sommerkamp H, Rupprecht M, Bruggmoser G, Wannenmacher M.
    Journal: Urologe A; 1988 Mar; 27(2):117-22. PubMed ID: 3376370.
    Abstract:
    Clinical followup of 52 patients treated with I-125 implants for localized prostatic cancer demonstrated local control in 85% and failure in 15%. Determining factors for local control or failure were analyzed and underline that homogeneous dose distribution is the most important factor for local control in interstitial radiotherapy. With the use of I-125 seeds this can only be achieved in small-volume (T2) stages with refined technique. For larger tumor volumes (T3) an external boost or the use of other radionuclides is preferable.
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