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Title: [Observation of therapeutic effect on coronavirus disease 2019 with insomnia in treatment with baduanjin and auricular point sticking therapy].
Author: Yang C, Ma Y, Mei JH, Gong X, Wang M, Liu K.
Journal: Zhongguo Zhen Jiu; 2021 Mar 12; 41(3):243-6. PubMed ID: 33798303.
Abstract:
OBJECTIVE: To compare the clinical therapeutic effect on coronavirus disease 2019 (COVID-19) with insomnia between the combined treatment of baduanjin and auricular point sticking therapy and the medication with oral estazolam on the base of the conventional treatment. METHODS: A total of 90 patients with COVID-19 accompanied with insomnia were randomly divided into an observation group (45 cases, 3 cases dropped off) and a control group (45 cases). In the observation group, baduanjin, a traditional Chinese fitness activity, was practiced everyday. Besides, auricular point sticking therapy was exerted at ear-shenmen (TF 4), subcortex (AT 4), heart (CO 15), occiput (AT 3), etc. These auricular points were pressed and kneaded three times a day, 30 s at each point each time, consecutively for 12 days. In the control group, estazolam tablets were prescribed for oral administration, 1 mg, once daily, consecutively for 12 days. Before and after treatment, the score of Pittsburgh sleep quality index (PSQI), the score of self-rating anxiety scale (SAS), the score of self-rating depression scale (SDS) and the score of symptoms in traditional Chinese medicine (TCM) were observed in the two groups and the clinical therapeutic effect was evaluated. RESULTS: After treatment, the scores of every item and the total scores in PSQI were all reduced as compared with those before treatment in the two groups (P<0.01). The scores of sleep time and sleep efficiency in the observation group were lower than those in the control group after treatment (P<0.05). SAS scores and SDS scores in the observation group and SAS score in the control group after treatment were all reduced as compared with those before treatment (P<0.01), and SDS score in the observation group was lower than that in the control group (P<0.01). After treatment, in the observation group, the score of each of the symptoms of TCM, i.e. unsound sleep, irritability and hot temper, profuse sputum and sticky feeling in the mouth, bitter taste in the mouth and foul breath, abdominal distention and poor appetite, as well as lassitude was reduced as compared with that before treatment successively (P<0.01), and the scores aforementioned (excepted for the unsound sleep) in the observation group were all lower than the control group (P<0.05). The total effective rates were 83.3% (35/42) in the observation group and 84.4% (38/45) in the control group, without statistical difference in comparison (P>0.05). CONCLUSION: The combined treatment of baduanjin and auricular point sticking therapy improves sleep quality, the conditions of anxiety and depression and the symptoms in TCM for patients of COVID-19 with insomnia. The therapeutic effect of this combined treatment is better than the oral administration of estazolam. 目的：在常规治疗基础上，比较八段锦联合耳穴贴压与口服艾司唑仑治疗新型冠状病毒肺炎（简称“新冠肺炎”）伴失眠的临床疗效。方法：将90例新冠肺炎伴失眠患者随机分为观察组(45例，脱落3例)和对照组(45例)。观察组每天练习八段锦1次，并进行耳穴贴压，穴取神门、皮质下、心、枕等，每日按揉3次，每次每穴30 s，连续治疗12 d。对照组口服艾司唑仑片1 mg，每日1次，连续治疗12 d。观察两组治疗前后匹兹堡睡眠质量指数（PSQI）评分、焦虑自评量表（SAS）评分、抑郁自评量表（SDS）评分、中医证候评分的变化，并评定临床疗效。结果：治疗后两组PSQI各项评分及总分均较治疗前降低（P<0.01），观察组治疗后睡眠时间、睡眠效率评分低于对照组（P<0.05）。治疗后观察组SAS、SDS评分及对照组SAS评分均较治疗前降低（P<0.01），观察组SDS评分低于对照组（P<0.01）。治疗后观察组睡眠不安、心烦易怒、痰多口黏、口苦口臭、腹胀纳差、乏力评分较治疗前降低（P<0.01），且观察组以上（除睡眠不安外）评分均低于对照组（P<0.05）。观察组总有效率为83.3%（35/42），对照组为84.4%(38/45)，组间比较差异无统计学意义(P>0.05)。结论：八段锦联合耳穴贴压可以改善新冠肺炎伴失眠患者的睡眠质量、焦虑抑郁状态和中医证候，疗效优于口服艾司唑仑。.

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