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  • Title: [Bushen Tiaodu Yizhi acupuncture combined with computer-assisted cognitive training for post stroke cognitive impairment: a randomized controlled trial].
    Author: Zheng CJ, Xia WG, Duan C, Li ZL, Li QL.
    Journal: Zhongguo Zhen Jiu; 2021 Mar 12; 41(3):247-51. PubMed ID: 33798304.
    Abstract:
    OBJECTIVE: To explore the effect of Bushen Tiaodu Yizhi acupuncture combined with computer-assisted cognitive training on the recovery of cognitive function and activities of daily living in patients with post stroke cognitive impairment. METHODS: A total of 98 patients with post stroke cognitive impairment were randomized into an observation group (50 cases, 6 cases dropped off) and a control group (48 cases, 5 cases dropped off). Both groups were treated with conventional treatment, such as computer-assisted cognitive training. On the basis of the conventional treatment, Bushen Tiaodu Yizhi acupuncture at Taixi (KI 3), Sanyinjiao (SP 6), Shuigou (GV 26), Baihui (GV 20), ect. was given in the observation group. In the control group, acupuncture at acupoints of limbs was given. The treatment was given once a day, 5 times a week for 8 weeks. Before and after treatment, the scores of Montreal cognitive assessment (MoCA) scale, modified Barthel index (MBI) and stroke syndrome of TCM scale were used to evaluate the cognitive function, activities of daily living and syndrome of TCM in the two groups. The latency and amplitude of P300 were detected by electromyographs and evoked response instrument. And the clinical efficacy was evaluated in the two groups. RESULTS: Compared before treatment, the MoCA and MBI scores were increased (P<0.01), and the scores of stroke syndrome of TCM scale were decreased (P<0.01) after treatment in the two groups. After treatment，the MoCA and MBI scores in the observation group were higher than the control group (P<0.01, P<0.05), and the score of stroke syndrome of TCM scale was lower than the control group (P<0.05). Compared before treatment, the latency of P300 was shortened and amplitude was prolonged after treatment in the two groups (P<0.01). After treatment, in the observation group, the latency of P300 was shorter, and amplitude was longer than the control group (P<0.01). The effective rate was 86.4% (38/44) in the observation group, which was higher than 67.4% (29/43) in the control group (P<0.01). CONCLUSION: Bushen Tiaodu Yizhi acupuncture combined with computer-assisted cognitive training could improve the cognitive function of patients with post stroke cognitive impairment. 目的：探讨“补肾调督益智”针刺联合计算机辅助认知训练对卒中后认知功能障碍（PSCI）患者认知功能及日常生活能力恢复的影响。方法：98例卒中后认知功能障碍患者随机分为观察组（50例，脱落6例）和对照组（48例，脱落5例）。两组均予计算机辅助认知训练等常规治疗，在此基础上，观察组予“补肾调督益智”针刺治疗，穴取太溪、三阴交、水沟、百会等；对照组予肢体针刺治疗，每日1次，每周5次，连续8周。治疗前后分别采用蒙特利尔认知评估（MoCA）量表、改良Barthel指数量表（MBI）及中风病中医证候学量表评分对患者认知功能、日常生活活动能力及中医证候进行评定，采用肌电诱发电位仪检测P300的潜伏期及波幅，并评定两组临床疗效。结果：与治疗前比较，两组患者治疗后MoCA、MBI评分提高（P<0.01），中风病中医证候学量表评分降低（P<0.01）；治疗后，观察组患者MoCA、MBI评分高于对照组（P<0.01，P<0.05），中风病中医证候学量表评分低于对照组 （P<0.05）。与治疗前比较，两组患者治疗后P300潜伏期缩短、波幅延长（P<0.01）；治疗后观察组P300潜伏期短于对照组，波幅长于对照组（P<0.01）。观察组有效率为86.4%（38/44），高于对照组的67.4%（29/43，P<0.01）。结论：“补肾调督益智”针刺联合计算机辅助认知训练有助于提高PSCI患者认知功能及日常生活能力。.
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