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  • Title: [Transcerebral electrophoresis of L-DOPA in the combined treatment of the hyperkinetic form of infantile cerebral palsy].
    Author: Kevlishvili DA, Shubladze LN, Kvitsaridze DA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1988; 88(3):58-61. PubMed ID: 3381615.
    Abstract:
    The authors present a detailed description of transcerebral electrophoresis of L-DOPA conducted in 20 patients aged 9 months to 12 years suffering from a hyperkinetic form of childhood cerebral paralysis. Each patient received 10 sessions. The results of the treatment were assessed by a 5-point score system. Diminution of involuntary movements by 1 point was observed in 1 patient, by 2 points in 10 patients, by 3 points in 7 patients and by 4 points in 1 patient; in one case no positive results were noted. Muscular dystonia and the severity of tonic reflexes decreased in all patients; voluntary movements also improved. Treatment with transcerebral electrophoresis of L-DOPA was well tolerated and was not associated with side-effects.
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