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  • Title: Cerebrospinal fluid pleocytosis following simple, complex partial, and generalized tonic-clonic seizures.
    Author: Devinsky O, Nadi S, Theodore WH, Porter RJ.
    Journal: Ann Neurol; 1988 Apr; 23(4):402-3. PubMed ID: 3382177.
    Abstract:
    We observed postictal pleocytosis in 7 of 62 cerebrospinal fluid specimens obtained from 27 patients with epilepsy. Each patient had a known seizure disorder; none had any other cause for the pleocytosis. The maximum number of leukocytes was 12/mm3; the maximum number of erythrocytes was 190/mm3. Postictal pleocytosis was more common in samples obtained within 12 hours of the last seizure. Although previous studies have emphasized that pleocytosis is more common after repetitive generalized tonic-clonic seizures, we found increased leukocyte counts in cerebrospinal fluid after single simple, complex partial, or generalized tonic-clonic seizures.
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