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  • Title: Developmental expression of proenkephalin mRNA in rat striatum and in striatal cultures.
    Author: Schwartz JP, Simantov R.
    Journal: Brain Res; 1988 May 16; 468(2):311-4. PubMed ID: 3382962.
    Abstract:
    Proenkephalin mRNA shows a biphasic developmental profile in rat striatum, with an initial peak at postnatal day 2, a decline to embryonic levels by day 7, and a second increase to adult levels over the course of the second to 4th week after birth. The same 4-fold increase is seen in cultured striatal neurons, over the same time course but without a biphasic response. Cultured fetal glia also contain proenkephalin mRNA.
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