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  • Title: [Dynamic contrast medium studies with flash sequences in nuclear magnetic resonance tomography of the breast].
    Author: Heywang SH, Hilbertz T, Pruss E, Wolf A, Permanetter W, Eiermann W, Lissner J.
    Journal: Digitale Bilddiagn; 1988 Mar; 8(1):7-13. PubMed ID: 3383539.
    Abstract:
    In this study the dynamic contrast behavior after Gd-DTPA of different breast tissues and tumors has been investigated with a series of T1-weighted FLASH-sequences during the first 5 minutes after the application of Gd-DTPA. The results of these dynamic FLASH-measurements have been compared to the results of the SE-sequences 6-10 and 11-15 minutes after Gd-DTPA in 40 patients with 54 different breast tissues. It could be shown that in a number of cases a better differentiation (e.g. DD between carcinomas and proliferative dysplasia) was possible on FLASH-scans early after contrast medium than on the late SE-scans. Only the distinction between non-proliferative and proliferative dysplasia was better on the late SE-scans. Evaluation of the enhancement dynamics may be helpful in some cases as an additional information. Further investigations are necessary to confirm these findings and to assess their value.
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