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Title: Analysis of chromium-51 release assay data using personal computer spreadsheet software. Author: Lefor AT, Steinberg SM, Wiebke EA. Journal: Comput Biomed Res; 1988 Jun; 21(3):268-75. PubMed ID: 3383556. Abstract: The Chromium-51 release assay is a widely used technique to assess the lysis of labeled target cells in vitro. We have developed a simple technique to analyze data from Chromium-51 release assays using the widely available LOTUS 1-2-3 spreadsheet software. This package calculates percentage specific cytotoxicity and lytic units by linear regression. It uses all data points to compute the linear regression and can determine if there is a statistically significant difference between two lysis curves. The system is simple to use and easily modified, since its implementation requires neither knowledge of computer programming nor custom designed software. This package can help save considerable time when analyzing data from Chromium-51 release assays.[Abstract] [Full Text] [Related] [New Search]