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Title: A novel ganglioside in dogfish brain. Occurrence of a trisialoganglioside with a sialic acid linked to N-acetylgalactosamine. Author: Nakamura K, Inagaki F, Tamai Y. Journal: J Biol Chem; 1988 Jul 15; 263(20):9896-900. PubMed ID: 3384822. Abstract: A novel trisialoganglioside has been isolated from dogfish (Squalus acanthias) brain. From the results of gas chromatography-mass spectrometric analysis of methylated sugars, enzymatic hydrolysis, fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance analysis, its structure was concluded to be (formula; see text) This is the first report of the occurrence of a ganglioside with 3 sialic acid residues separately linked to its gangliotetraosyl backbone.[Abstract] [Full Text] [Related] [New Search]