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Title: Solid-phase radioimmunoassay for detection of antibodies to myelin basic protein. Author: Randolph DH, Kibler RF, Fritz RB. Journal: J Immunol Methods; 1977; 18(3-4):215-24. PubMed ID: 338832. Abstract: A solid-phase double-antibody radioimmunoassay was developed for the detection of anti-myelin basic protein (BP) in sera. Antigen was adsorbed to glass test tubes, reacted with rat anti-BP sera, followed by 125I-labeled rabbit anti-rat IgG. This assay was capable of detection of specific antibody at low nanogram per ml levels, was technically simple, and the results correlated well with established procedures.[Abstract] [Full Text] [Related] [New Search]