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  • Title: Boerhaave's syndrome after pentazocine-induced vomiting in a 21-year-old male with asthma: a case report.
    Author: Awofisoye OI, Olalekan OE, Anumenechi N, Onwukpa F.
    Journal: Pan Afr Med J; 2021; 38():74. PubMed ID: 33889240.
    Abstract:
    Boerhaave's syndrome is an uncommon syndrome characterized by spontaneous rupture of the oesophagus with a high mortality rate. While excessive alcohol intake and binge-eating are the classic precipitants of this syndrome, medication-induced vomiting causing Booerhave's is quite uncommon. Traditionally managed operatively, conservative management is being increasingly reported in selected cases. We report the case of 21-year-old male with who developed sudden onset chest pain and dyspnoea after pentazocine induced vomiting. He was referred after lack of response to initial treatment for acute severe asthma. A chest CT scan showed pneumomediastinum, subcutaneous emphysema and oesophageal tear. He was managed conservatively with oxygen therapy, nil per mouth and antibiotics with improvement of symptoms and discharge after 8 days.
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